ChemInform Abstract: An Efficient Synthesis of Styrenyl Enamides from 4-Aryl-2-oxazolidinones in the Presence of Strong Base

Efficient synthesis of styrenyl enamides can be achieved from the corresponding 4-aryl-2-oxazolidinones, 2-thioxooxazolidines, and 2-thioxothiazolidines in the presence of the strong base lithium diisopropylamine. The reaction proceeded efficiently to achieve the enamides in good to excellent yields (up to 92%). This reaction provides an easy, rapid, and good-yielding method for the synthesis of styrenyl enamides.