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A site-differentiated [4Fe–4S] cluster controls electron transfer reactivity of Clostridium acetobutylicum [FeFe]-hydrogenase I

Authors :
Carolyn E. Lubner
Jacob H. Artz
David W. Mulder
Aisha Oza
Rachel J. Ward
S. Garrett Williams
Anne K. Jones
John W. Peters
Ivan I. Smalyukh
Vivek S. Bharadwaj
Paul W. King
Source :
Chemical Science. 13:4581-4588
Publication Year :
2022
Publisher :
Royal Society of Chemistry (RSC), 2022.

Abstract

Histidine coordination of the distal [4Fe–4S] cluster in [FeFe]-hydrogenase was demonstrated to tune the cluster spin-states, spin-pairing and surrounding molecular orbitals to enable more facile electron transfer compared to cysteine coordination.

Subjects

Subjects :
General Chemistry

Details

ISSN :
20416539 and 20416520
Volume :
13
Database :
OpenAIRE
Journal :
Chemical Science
Accession number :
edsair.doi...........b177def6170e81d0039d0dcbeeda3c2c
Full Text :
https://doi.org/10.1039/d1sc07120c