Preparation of Optically Active (S)-2-Aminoalkylphosphonic Acids from (S)-Amino Acids without Racemization

Optically active (S)-2-aminopropylphosphonic and (S)-2-amino-4-methylpentylphosphonic acids were synthesized from commercially available chiral α-amino acids [(S)-(+)-alanine and (S)-(+)-leucine] without racemization.