ChemInform Abstract: Enantioselective Synthesis of Angularly Substituted 1-Azabicyclic Rings: Coupled Dynamic Kinetic Epimerization and Chirality Transfer

Authors :: Zachary D. Aron
Jocelyn Wang
Tatsuya Ito
Larry E. Overman
Tircia L. May
Source :: ChemInform. 45
Publication Year :: 2014
Publisher :: Wiley, 2014.
Abstract: This method starts from substrates with high enantiomeric excesses and proceeds with excellent chirality transfers (usually ≥ 96%) yielding products with up to three stereocenters.

Subjects :: Chemistry
Stereochemistry
Enantioselective synthesis
Epimer
General Medicine
Enantiomer
Kinetic energy
Chirality (chemistry)
Stereocenter

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