ChemInform Abstract: Short-Step Synthesis of the Ergot Alkaloids, (±)-Norchanoclavine-I, (±)-Chanoclavine-I, (±)-Isochanoclavine-I and (±)-Agroclavine

The simple total synthesis of the ergot alkaloids, (±)-norchanoclavine-I, (±)-chanoclavine-I, (±)-isochanoclavine-I, and (±)-agroclavine was achieved by a practical and common synthesis method. A new regio-selective oxidation of the Z-methyl group of the isoprenyl system with selenium dioxide is described.