A FUNDAMENTAL, RECIPROCAL RELATIONSHIP BETWEEN MYELOID AND LYMPHOID TISSUES

Progress in the solution of the problems of disease in man must depend to a considerable degree on fundamental progress in the recognition and interpretation of alterations in disturbed physiologic equilibriums. It may be true that physiology "has its own problems, great in number and enormous in complexity, and those of disease are not among them."1Nevertheless, experience has established that the origin and explanation of many abnormal states may be traced to deranged physiologic processes, and more particularly to disturbed physiologic equilibriums. Granted that this is beyond the scope of pure physiologic research, the recognition of states of physiologic imbalance and of pathologic alterations produced in the tissues by this imbalance then becomes an important concern of the clinical investigator. That this "borderline" territory between physiology and medicine has proved a very fruitful field for clinical investigation, in one direction at least, is quite apparent when one reviews