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Synthesis and evaluation of peptidyl vicinal tricarbonyl monohydrates as inhibitors of hydrolytic enzymes
- Source :
- The Journal of Organic Chemistry. 58:4785-4787
- Publication Year :
- 1993
- Publisher :
- American Chemical Society (ACS), 1993.
-
Abstract
- Peptidyl vicinal tricarbonyls, prepared from N-protected di- and tripeptides by reaction of the carboxylic acid residues with ylides followed by oxidation, have been shown to be potent inhibitors of serine proteases
Details
- ISSN :
- 15206904 and 00223263
- Volume :
- 58
- Database :
- OpenAIRE
- Journal :
- The Journal of Organic Chemistry
- Accession number :
- edsair.doi...........aef166f44ec122a10f3c1237b8fa55dc