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Searching for enhanced iron fortification of formula milk via nanoparticles and Isotope Pattern Deconvolution
- Source :
- Spectrochimica Acta Part B: Atomic Spectroscopy. 148:165-171
- Publication Year :
- 2018
- Publisher :
- Elsevier BV, 2018.
-
Abstract
- Nanoparticles (NPs) of 57Fe(III) oxo-hydroxide have been investigated for formula milk iron fortification. The body iron status of lactating rats was evaluated by analyzing iron content in all iron compartments (functional, transport and storage). Results were compared with a non‑iron fortified rat group (NF) and a rat group fortified with FeSO4. Intestinal iron (57Fe) absorption observed in rats using the synthesized NPs was 91% (similar to the obtained for FeSO4), and their total iron levels in the functional compartment were the highest, while similar values were observed in the other iron compartments for both iron fortified groups. Exogenous 57Fe incorporation from NPs was always higher than 56% in all the analyzed iron compartments. Interestingly, higher than those observed for other physicochemical forms assayed for formula milk fortification. This work has shown that 57Fe from the assayed NPs is efficiently incorporated keeping appropriate iron levels, protecting from possible body iron deficiency.
- Subjects :
- 0301 basic medicine
Ferrous sulphate
Isotope
Chemistry
Iron levels
Nanoparticle
Iron fortification
02 engineering and technology
Absorption (skin)
021001 nanoscience & nanotechnology
Atomic and Molecular Physics, and Optics
Analytical Chemistry
Body iron
03 medical and health sciences
030104 developmental biology
Iron content
Food science
0210 nano-technology
Instrumentation
Spectroscopy
Subjects
Details
- ISSN :
- 05848547
- Volume :
- 148
- Database :
- OpenAIRE
- Journal :
- Spectrochimica Acta Part B: Atomic Spectroscopy
- Accession number :
- edsair.doi...........ae56c8f7e84e04865d400271085f0f9c