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Involvement of FcɛR1β gene polymorphisms in susceptibility to atopy in Korean children with asthma

Authors :
Eun Soo Kim
Kyu-Earn Kim
Myung Hyun Sohn
Jongeun Lee
Seung-Hyun Kim
Eun Soon Shin
Hae-Sim Park
Kyung Won Kim
Source :
European Journal of Pediatrics. 168:1483-1490
Publication Year :
2009
Publisher :
Springer Science and Business Media LLC, 2009.

Abstract

Introduction IgE-dependent activation of mast cells and basophils through the high-affinity IgE receptor (FcɛR1) is involved in the pathogenesis of allergen-induced immune responsiveness in atopic disease including bronchial asthma.

Details

ISSN :
14321076 and 03406199
Volume :
168
Database :
OpenAIRE
Journal :
European Journal of Pediatrics
Accession number :
edsair.doi...........ac9100e2ac04df716691de8a8777fb82
Full Text :
https://doi.org/10.1007/s00431-009-0960-x