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Chemical Constituents of the Roots of Phlomis betonicoides and Their Anti-Rotavirus Activity
- Source :
- Chemistry of Natural Compounds. 57:864-868
- Publication Year :
- 2021
- Publisher :
- Springer Science and Business Media LLC, 2021.
-
Abstract
- Two new isobenzofuranone derivatives (1 and 2) together with six known compounds (3–8) were isolated from the roots of Phlomis betonicoides, a highly sweet plant in China. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1–8 were tested for their anti-rotavirus activity. The results showed that compounds 1–8 exhibited potent anti-rotavirus activity with therapeutic index value 7.5–16.4.
Details
- ISSN :
- 15738388 and 00093130
- Volume :
- 57
- Database :
- OpenAIRE
- Journal :
- Chemistry of Natural Compounds
- Accession number :
- edsair.doi...........ac53618b11acfaef4ecb8165b13383ce