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Store-operated Ca2+ entry inhibition ameliorates high glucose and ANG II-induced podocyte apoptosis and mitochondrial damage

Authors :
Yu Tao
Parisa Yazdizadeh Shotorbani
Denise Inman
Paromita Das-Earl
Rong Ma
Source :
American Journal of Physiology-Renal Physiology. 324:F494-F504
Publication Year :
2023
Publisher :
American Physiological Society, 2023.

Abstract

This study tested the hypothesis that overwhelming store-operated Ca2+ entry is a novel mechanism contributing to high glucose- and angiotensin II-induced podocyte apoptosis and mitochondrial injury.

Subjects

Subjects :
Physiology

Details

ISSN :
15221466 and 1931857X
Volume :
324
Database :
OpenAIRE
Journal :
American Journal of Physiology-Renal Physiology
Accession number :
edsair.doi...........abf0d1d7014483358163d8436c1507d0
Full Text :
https://doi.org/10.1152/ajprenal.00297.2022