ChemInform Abstract: Base-Promoted Domino Reaction for the Synthesis of 2,3-Disubstituted Indoles from 2-Aminobenzaldehyde/2-Amino Aryl Ketones, Tosylhydrazine, and Aromatic Aldehydes

A base-promoted domino reaction to synthesize the 2,3-disubstituted indoles from 2-aminobenzaldehyde/2-amino aryl ketones, tosylhydrazine, and aromatic aldehydes has been developed. This strategy provides a simple and beneficial way for the construction of 2,3-disubstituted indole compounds from readily available starting materials under mild conditions.