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- Source :
- Clinical Cardiology.
-
Abstract
- BACKGROUND Sarcoidosis is a multisystem granulomatous disease of not sufficiently understood origin. Some patients develop cardiac involvement in course of the disease which is mostly responsible for adverse outcome. In addition to complications like high degree atrioventricular (AV) block or ventricular tachyarrhythmias, there is a certain percentage of patients developing atrial tachyarrhythmias. Data is limited and the role of catheter ablation uncertain. Therefore, we studied sarcoid patients who presented with supraventricular tachyarrhythmias. HYPOTHESIS Treatment and ablation of supraventricular tachycardia could be hampered by inflammation in patients with cardiac sarcoidosis. METHODS We enrolled 37 consecutive patients with cardiac sarcoidosis who presented with atrial tachyarrhythmias and underwent an electrophysiologic study over a period of 6 years (03/2013-04/2019). In total, 16 catheter ablations for atrial tachyarrhythmias were performed. Mean follow-up duration was 2.5 years. RESULTS Most common ablation performed was cavo-tricuspid isthmus ablation for typical atrial flutter in seven patients (54%). Pulmonary vein isolation for treatment of atrial fibrillation (AF) was performed in five patients (38%). Two patients received slow-pathway modulation for treatment of recurrent atrioventricular nodal reentry tachycardia (AVNRT). All but two patients with AF had no clinical recurrence during follow-up. Two patients had recurrence of AF but still reported markedly improved european heart rhythm association (EHRA) class. Periprocedural safety was very high. There were no adverse events related to the ablation procedure. One patient died during follow-up in the presence of electrical storm. CONCLUSION Catheter ablations of supraventricular tachycardias seem to be safe and effective in patients with cardiac sarcoidosis. Outcome is comparable to patients without inflammatory heart disease, although data from larger patient collectives are mandatory to make recommendations in this special entity.
- Subjects :
- medicine.medical_specialty
Heart disease
business.industry
medicine.medical_treatment
Atrial fibrillation
Catheter ablation
General Medicine
030204 cardiovascular system & hematology
medicine.disease
Ablation
Pulmonary vein
03 medical and health sciences
Catheter
0302 clinical medicine
Typical atrial flutter
Internal medicine
cardiovascular system
medicine
Cardiology
cardiovascular diseases
030212 general & internal medicine
Supraventricular tachycardia
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 01609289
- Database :
- OpenAIRE
- Journal :
- Clinical Cardiology
- Accession number :
- edsair.doi...........ab21c58ed561edc0f0ef6a05a3225cc0