Thrombomodulin Alfa for Acute Exacerbation of Idiopathic Pulmonary Fibrosis. A Randomized, Double-Blind Placebo-controlled Trial

Authors :: Tetsuji Kawamura
Sakae Homma
Hiroyuki Taniguchi
Arata Azuma
Yoshikazu Inoue
Noriho Sakamoto
Kiminori Fujimoto
Masaki Okamoto
Natsuki Yamamori
Masahito Ebina
Jun Araya
Yoshio Taguchi
Shinji Abe
Yoshihito Yamada
Mitsuhiro Abe
Yasuhiro Kondoh
Kenji Tsushima
Machiko Arita
Hiroyoshi Yamauchi
Joe Shindoh
Susumu Sakamoto
Shinyu Izumi
Jun Tagawa
Yasuo Matsuzawa
Hiroshi Ishii
Masahiro Aoshima
Takafumi Suda
Naozumi Hashimoto
Takeshi Johkoh
Yuji Tohda
Kazuma Kishi
Koji Bessho
Takashi Ogura
Keisuke Tomii
Takefumi Saito
Kazuya Ichikado
Source :: American Journal of Respiratory and Critical Care Medicine. 201:1110-1119
Publication Year :: 2020
Publisher :: American Thoracic Society, 2020.
Abstract: Rationale: Acute exacerbation during the course of idiopathic pulmonary fibrosis causes a poor prognosis. Coagulation abnormalities and endothelial damage are involved in its pathogenesis. Thrombom...

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