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ChemInform Abstract: Selective Cyclization of Arylnitrones to Indolines under External Oxidant-Free Conditions: Dual Role of Rh(III) Catalyst in the C-H Activation and Oxygen Atom Transfer
- Source :
- ChemInform. 46
- Publication Year :
- 2015
- Publisher :
- Wiley, 2015.
-
Abstract
- The first example of Rh(III)-catalyzed cyclization of arylnitrones to indolines under external oxidant-free conditions is presented. An intermolecular coupling of arylnitrones with internal alkynes is made possible by the dual role of the Cp*Rh(III) catalyst mediating both the C–H bond activation and O-atom transfer. Synthetically important and pharmacologically privileged indoline derivatives were obtained in good yields with high diastereoselectivity.
Details
- ISSN :
- 09317597
- Volume :
- 46
- Database :
- OpenAIRE
- Journal :
- ChemInform
- Accession number :
- edsair.doi...........aadbeb00ac425e2373badd71b99bff0b