Fetal hemoglobin and clinical parameters in patients of sickle cell disease

Objective: To corelate the Hb F levels with clinical parameters of patients with sickle cell disease and sickle beta thalassemia. Study Design: Cross Sectional study. Setting: Chughtai Institute of Pathology. Period: June 2020 to December 2021. Material & Methods: A total of 150 diagnosed cases of sickle cell disease and sickle beta thalassemia were included in the study. Hemoglobin electrophoresis was performed and Hb F levels were noted. Detailed history of patients regarding their complications was taken. Data analysis was done using SPSS 23.0. Correlation of Hb F with Hb levels, splenomegaly, other symptoms and number of transfusions required was observed using Pearson test taking P value