Trypanocidal components ofPluchea quitoc L

Four compounds active against the epimastigote forms of Trypanosoma cruzi, the causative agent of Chagas' disease, were isolated from the hexane extract of Pluchea quitoc L. (Compositae). The flavone casticin (1), identified on the basis of its spectroscopic characteristics, along with PQU19B, 19G and 28A, the structures of which are in the process of identification, did not show significant activity against the infective bloodstream trypomastigote forms of the parasite