TCT-561 Splenic Artery Denervation: Rationale, Feasibility, and Early Pre-Clinical Experience in a Porcine Model of Inflammatory Arthritis

Authors :: Raffaele Melidone
Peter Markham
Anna Spognardi
Abraham R. Tzafriri
Brett Zani
Mazen Albaghdadi
John Keating
Fernando Gacia-Polite
Source :: Journal of the American College of Cardiology. 72:B225
Publication Year :: 2018
Publisher :: Elsevier BV, 2018.
Abstract: The spleen plays an important role in the immune response to inflammatory conditions including cancer, myocardial infarction and atherosclerosis. Device-based neuromodulation of the spleen’s neural pathways is an emerging therapeutic approach to regulating the immune response in various

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