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A Study of the Effect of the Manufacturers Advised Recalculation of the High Sensitivity Troponin T Assay on the Early Detection of Acute Myocardial Infarction in Patients Presenting to the Emergency Department

Authors :
Carel J. Pretorius
Jillian R Tate
Jacobus P.J. Ungerer
Louise Cullen
William A. Parsonage
Arvin Lamanna
Jaimi H. Greenslade
C. Hammett
Kevin Chu
Anthony F T Brown
Source :
Heart, Lung and Circulation. 22:S208
Publication Year :
2013
Publisher :
Elsevier BV, 2013.

Abstract

index admission. 313 (19.7%) patients had an elevated hscTnI value at 0 or 2 h and 494 (31.1%) patients had an elevated hs-cTnT value. Sensitivity for AMI was equivalent between hs-cTnI and hs-cTnT (96.2% versus 94.8%, p= 0.61). Specificity for AMI was higher using hs-cTnI at zero (93.6% versus 80.5%, p< 0.01) and two hours (92.8% vs. 80.8%, p< 0.01). Conclusions: The hs-cTnI and hs-cTnT assays were equally sensitive forearlydiagnosisofAMIbut thehs-cTnI assay was significantly more specific. http://dx.doi.org/10.1016/j.hlc.2013.05.494

Details

ISSN :
14439506
Volume :
22
Database :
OpenAIRE
Journal :
Heart, Lung and Circulation
Accession number :
edsair.doi...........a8298146ce79052a40215b1ca78926e9