Association Between Air Pollution and Case-Specific Mortality in North-Eastern Part of Poland. Case-Crossover Study with 4,500,000 Person-Years of Follow-Up (PL-PARTICLES Study)

Background: Recent studies have reported associations between air pollution and daily mortality. The majority of them are conducted in highly polluted areas. Therefore, we aimed to assess the short-term impact of air pollution on cardiovascular (CVD)-, coronary artery-related (CAD)-, and cerebrovascular-related (CbVD) mortality in moderately polluted cities. Methods: The analysis with a time-stratified case-crossover design was performed. Findings: The interquartile range (IQR) increase in PM2.5 (OR 1×036, 95%CI 1×016–1×056, P