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ChemInform Abstract: Azido Glycols: Potent, Low Molecular Weight Renin Inhibitors Containing an Unusual Post Scissile Site Residue

Authors :
Hugh N. Nellans
Keith W. Woods
Jerome Cohen
D. J. Hoffman
Saul H. Rosenberg
Jacob J. Plattner
R. A. Pyter
Thomas J. Perun
S. G. Spanton
Herman H. Stein
H. D. Kleinert
David A. Egan
Source :
ChemInform. 20
Publication Year :
1989
Publisher :
Wiley, 1989.

Abstract

Basic hydrolysis of the oxazolidinone (I) followed by N-protection produces the allylic alcohol (IIb) which is converted to the diol (IV) by hydroboration.

Details

ISSN :
09317597
Volume :
20
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi...........a7dd627880ac5a7e98909f15287167f6
Full Text :
https://doi.org/10.1002/chin.198949112