Analysis of single circulating tumor cells (CTCs) to identify resistance mutations to ALK-inhibitors in both ALK-gene and bypass oncogenic pathways

Authors :: Benjamin Besse
Claudio Forcato
Aurelie Honore
Françoise Farace
Emma Pailler
Pauline Queffelec
Yann Lécluse
Nicolò Manaresi
Claudio Nicotra
Ludovic Lacroix
Marianne Oulhen
Maud Ngo-Camus
David Planchard
Jordi Remon
Jean-Charles Soria
Virginie Marty
Laura Mezquita
Vincent Faugeroux
Mélanie Laporte
Source :: Journal of Clinical Oncology. 36:12038-12038
Publication Year :: 2018
Publisher :: American Society of Clinical Oncology (ASCO), 2018.
Abstract: 12038Background: Non-invasive methods including CTCs are crucial to develop for the implementation of precision medicine in the treatment of NSCLC. ALK-rearranged NSCLC patients develop resistance ...

Subjects :: 0301 basic medicine
Cancer Research
business.industry
Precision medicine
respiratory tract diseases
03 medical and health sciences
030104 developmental biology
0302 clinical medicine
Circulating tumor cell
030228 respiratory system
Oncology
hemic and lymphatic diseases
Cancer research
Medicine
Anaplastic lymphoma kinase
business
neoplasms

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