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Multiarmed Bandit Designs for Phase I Dose-Finding Clinical Trials With Multiple Toxicity Types
- Source :
- Statistics in Biopharmaceutical Research. 15:164-177
- Publication Year :
- 2021
- Publisher :
- Informa UK Limited, 2021.
-
Abstract
- The goal of a phase I dose-finding trial is to determine the dose level of a new drug with acceptable toxicity. The optimal dose level is determined by sequentially allocating patients to increasin...
Details
- ISSN :
- 19466315
- Volume :
- 15
- Database :
- OpenAIRE
- Journal :
- Statistics in Biopharmaceutical Research
- Accession number :
- edsair.doi...........a78a28eb874b61cfd006edd74b09ed09