Adrenergic and Anticholinergic Bronchodilators; Do They Act as Bronchospasmolytics? Perspectives in the development of anti-asthmatics

On the basis of recent experimental evidence the classical concept of bronchospasmogens and bronchospasmolytics is challenged, switching the emphasis from bronchial smooth muscle hyperreactivity to tracheal and bronchial mucosa hypersensitivity or irritability. Against the background of the revised views some possibilities for development of new anti-asthmatic agents are discussed.