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ChemInform Abstract: Synthesis and Evaluation of 1H-Pyrazolo(3,4-b)quinoxalines and 1-Aryl- 3-quinoxalinyl-1,2,4-triazole as Antibacterial Agent
- Source :
- ChemInform. 28
- Publication Year :
- 2010
- Publisher :
- Wiley, 2010.
-
Abstract
- Novel 1H-pyrazolo[3,4-b]quinoxalines (flavazoles) 14, 15 and 1-aryl-3-quinoxalinyl-1,2,4-triazole 17 were synthesized from the ester 11 via various hydrazones 12, 13 and 16. In the antibacterial screening test of compounds 12–17, compound 14 showed a relatively high antibacterial activity, wherein the MIC value was 25 μg/ml against Bacillus licheniformis KTCC 21425 and Cellulomonas sp. and 50 μg/ml against Salmonella typhimurium KCTC 1925 and Flavobacterium devolans.
Details
- ISSN :
- 09317597
- Volume :
- 28
- Database :
- OpenAIRE
- Journal :
- ChemInform
- Accession number :
- edsair.doi...........a729cfaaf642b4d674055d03db392d6d