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Phyto-Phospholipid Complexes: Innovative Approach to Enhance the Bioavailability and Therapeutic Efficacy of Herbal Extract

Authors :
Reenu Yadav
Shailesh Kumar Ghatuary
Avishikta Ray
Anju Singh
Pramod K. Biswal
Rakhi Mishra
Source :
Pharmaceutical and Biosciences Journal. :01-09
Publication Year :
2020
Publisher :
UK Journal of Pharmaceutical and Biosciences, 2020.

Abstract

The herbal drug are used extensively for the treatment of the various diseases by the globe. The minimum side effects of medicinal plants attract people for its medicinal uses. The conventional dosage form of herbal medicine has certain limitation like low absorption, reduced bioavailability and lower penetration across biological membrane, it decrease their uses. Hence the introduction of novel drug delivery system namely Phyto-Phospholipid Complexes techniques resolve all these issues of herbal extract or plant actives. This advance technology technique reduced dose to produce desired therapeutic effect, improved stability due to chemical linkage, ability to permeate through skin systematic targeting to transit from hydrophilic to lipophilic environment and improved pharmacokinetic parameters. This review summarizes the latest investigations regarding the possible application of Phytosomes complexes for therapy of different dieseases, their marketed formulation, mechanism of transportation through phytosome and future prospect. The prospectus of Phytosomes technique can suggest new directions and endless frontier as novel drug treatment.

Details

ISSN :
25820540
Database :
OpenAIRE
Journal :
Pharmaceutical and Biosciences Journal
Accession number :
edsair.doi...........a6a8b3aa5f6b08f1a09ebb6d47adfcf7
Full Text :
https://doi.org/10.20510/ukjpb/8/i4/1593521611