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Tandem deprotection-coupling of Nα-Alloc-amino acids by use of ternary systems Pd cat./PhSiH3/carboxy-activated amino acid
- Source :
- Tetrahedron Letters. 40:2505-2508
- Publication Year :
- 1999
- Publisher :
- Elsevier BV, 1999.
-
Abstract
- Nα-allyloxycarbonyl derivatives of amino acids undergo smooth coupling with various carboxy-activated partners when treated with phenylsilane (PhSiH3) in the presence of catalytic amounts of tetrakis-(triphenylphosphine) palladium.
- Subjects :
- inorganic chemicals
chemistry.chemical_classification
Stereochemistry
Organic Chemistry
chemistry.chemical_element
Peptide
Biochemistry
Catalysis
Amino acid
Acylation
chemistry.chemical_compound
chemistry
Phenylsilane
Drug Discovery
Organic chemistry
Triphenylphosphine
Ternary operation
Palladium
Subjects
Details
- ISSN :
- 00404039
- Volume :
- 40
- Database :
- OpenAIRE
- Journal :
- Tetrahedron Letters
- Accession number :
- edsair.doi...........a66eab8aa21a25c751339192e009cb5f
- Full Text :
- https://doi.org/10.1016/s0040-4039(99)00240-3