Guided optimization of a crystallization-induced diastereomer transformation to access a key navoximod intermediate

Authors :: Andrew J. Kukor
Frédéric St-Jean
Andreas Stumpf
Thomas C. Malig
Katarzyna A. Piechowicz
Kenji Kurita
Jason E. Hein
Source :: Reaction Chemistry & Engineering.
Publication Year :: 2023
Publisher :: Royal Society of Chemistry (RSC), 2023.
Abstract: The crystallization-induced diastereomer transformation of a precursor to navoximod was investigated using online HPLC and optimized with inline racemization.

Subjects :: Fluid Flow and Transfer Processes
Chemistry (miscellaneous)
Process Chemistry and Technology
Chemical Engineering (miscellaneous)
Catalysis

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