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OCT detection of neural activity in American cockroach nervous system
- Source :
- Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII.
- Publication Year :
- 2013
- Publisher :
- SPIE, 2013.
-
Abstract
- We show results of a project which focuses on detection of activity in neural tissue with Optical Coherence Tomography (OCT) methods. Experiments were performed in neural cords dissected from the American cockroach (Periplaneta americana L.). Functional OCT imaging was performed with ultrahigh resolution spectral / Fourier domain OCT system (axial resolution 2.5 μm). Electrical stimulation (voltage pulses) was applied to the sensory cercal nerve of the neural cord. Optical detection of functional activation of the sample was performed in the connective between the terminal abdominal ganglion and the fifth abdominal ganglion. Functional OCT data were collected over time with the OCT beam illuminating selected single point in the connectives (i.e. OCT M-scans were acquired). Phase changes of the OCT signal were analyzed to visualize occurrence of activation in the neural cord. Electrophysiology recordings (microelectrode method) were also performed as a reference method to demonstrate electrical response of the sample to stimulation.
- Subjects :
- Nervous system
Materials science
genetic structures
medicine.diagnostic_test
biology
Sensory system
biology.organism_classification
Signal
eye diseases
Microelectrode
Neural activity
Electrophysiology
medicine.anatomical_structure
Optical coherence tomography
medicine
sense organs
American cockroach
Biomedical engineering
Subjects
Details
- ISSN :
- 0277786X
- Database :
- OpenAIRE
- Journal :
- Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII
- Accession number :
- edsair.doi...........a5c09691a80f55b5ec8a89c53f1059ca