BIOACTIVE METABOLITES FROM MARINE MICROORGANISMS

Diverse arrays of new bioactive secondary metabolites have been isolated from marine microorganisms; and the number of publications in this area has greatly increased in recent years. In this review, the emphasis is placed on new compounds with antitumor, enzyme inhibitors, antivirus, and other bioactive metabolites from fungi, bacteria, actinomycetes, and cyanobacteria reported between 2000 and 2005. Supply is a major limitation in the development of marine bioproducts, and the methods for supplying these products are important. So in this review, the secondary major point is placed on the chemical synthetic studies. References of 390 structures and 263 citations are overall presented in this review.