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(R)-(+)-2-{[(3-Methyl-4-nitropyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole

Authors :
Manne Naga Raju
Peddy Vishweshwar
Naveenkumar Kolla
Rakeshwar Bandichhor
Neelam Uday Kumar
Source :
Acta Crystallographica Section E Structure Reports Online. 67:o2190-o2190
Publication Year :
2011
Publisher :
International Union of Crystallography (IUCr), 2011.

Abstract

The title compound, C14H12N4O3S, is an inter­mediate of Dexlansoprazole, a proton pump inhibitor (PPI) mainly developed for anti-ulcer activity. The absolute configuration of the title compound was determined as R. The crystal structure reveals that the mol­ecules form chains along the b axis through N—H⋯N and C—H⋯O hydrogen-bonded dimers. These chains are connected via weak C—H⋯O hydrogen bonds.

Details

ISSN :
16005368
Volume :
67
Database :
OpenAIRE
Journal :
Acta Crystallographica Section E Structure Reports Online
Accession number :
edsair.doi...........a491cb7e633b0ac73a5c948e2df4aa31
Full Text :
https://doi.org/10.1107/s1600536811029990