Materials in periodontal regenerative therapy: An overview

Periodontal diseases refer to periodontal ligament injury affecting all the supporting structure and, if left untreated, results in loss of the tooth. Periodontal regenerative therapies aim towards healing all the damaged periodontal tissues by not only restoring structure but also the functions. This review provides information of all the currently-used as well as advanced biomaterials for periodontal regeneration. During this advancing research, various regenerative therapies of periodontal apparatus, such as guided tissue regeneration (GTR), enamel matrix derivative, bone grafts, growth factor delivery, and the combination of cells and growth factors with matrix-based scaffolds have been implemented to restore lost tooth-supporting tissues, including periodontal ligament, alveolar bone, and cementum. This review has stated about the recent progresses of periodontal regeneration by means of tissue-engineering.