EXPERIENCE WITH ADMINISTRATION OF PLASMANATE IN SURGICAL PATIENTS

In order to relieve hypoproteinemia associated with Banti's syndrome and brought about by the application of pump-oxygenator for open heart surgery, Plasmanate (Cutter) has been administered to 3 cases of Banti's syndrome and 2 cases of open heart surgery with pump-oxygenator.The effect of Plasmanate on the patients with Banti's syndrome revealed increase of serum albumin, rise of A/G ratio, increase of urinary out-put, and marked improvement of edema following the administration. Administration of Plasmanate was also effective in preventing postoperative hypoproteinemia following open heart surgery with pump-oxygenator.Protein fraction of Plasmanate was analysed with the method of paper electrophoresis which revealed 4.8% of albumin on average with no trace of gamma-globulin. Side effect of Plasmanate following the administration has not been noticed up to the present time.