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Synthesis of condensed pyrrolo[b]pyrazines

Authors :
Yu. M. Volovenko
G. G. Dubinina
Source :
Chemistry of Heterocyclic Compounds. 35:1089-1093
Publication Year :
1999
Publisher :
Springer Science and Business Media LLC, 1999.

Abstract

Reaction of 2,3-dichloro-5,6-dicyanopyrazine with α-azahetarylacetonitriles gives α-(3-chloro-5,6-dicyanopyrazin-2-yl)-α-(2-azahetaryl)acetonitriles. Subsequent heating in pyridine causes an intramolecular cyclization to yield condensed pyrrolo[b]pyrazines.

Details

ISSN :
15738353 and 00093122
Volume :
35
Database :
OpenAIRE
Journal :
Chemistry of Heterocyclic Compounds
Accession number :
edsair.doi...........a3a3a7824e28be9bc748881cd9ebd8cd
Full Text :
https://doi.org/10.1007/bf02251802