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GW29-e1812 C1q/TNF-Related Protein 1 Promotes Vasodilatory Dysfunctions by Increasing Arginase 1 Activity and Uncoupling of Endothelial Nitric Oxide Synthase

Authors :
Xiaoqun Wang
Lu Lin
Source :
Journal of the American College of Cardiology. 72:C61
Publication Year :
2018
Publisher :
Elsevier BV, 2018.

Abstract

C1q/TNF-related protein (CTRP) 1 was initially identified as a paralog of adiponectin based on the similarity in C1q domain of these two proteins. Previously, we showed that CTRP1 promotes the development of atherosclerosis by increasing endothelial adhesiveness. Here, we sought to investigate

Details

ISSN :
07351097
Volume :
72
Database :
OpenAIRE
Journal :
Journal of the American College of Cardiology
Accession number :
edsair.doi...........a3127db46f93d8fca511fa5e3baa2ef6
Full Text :
https://doi.org/10.1016/j.jacc.2018.08.223