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Deformylation of indole and azaindole-3-carboxaldehydes using anthranilamide and solid acid heterogeneous catalyst via quinazolinone intermediate

Authors :
Nagaraju Muparappu
Ramesh Mudududdla
Sandip B. Bharate
Rammohan R. Yadav
Jaideep B. Bharate
Narsaiah Battini
Ram A. Vishwakarma
Source :
Tetrahedron Letters. 53:2222-2225
Publication Year :
2012
Publisher :
Elsevier BV, 2012.

Abstract

The deformylation of indole and azaindole-3-carboxaldehydes was achieved in the presence of anthranilamide and a solid acid heterogeneous catalyst under reflux conditions in 25–90% yield. The reaction proceeds via quinazolinone intermediate, which undergoes acid catalyzed cleavage to form deformylated product.

Details

ISSN :
00404039
Volume :
53
Database :
OpenAIRE
Journal :
Tetrahedron Letters
Accession number :
edsair.doi...........a129337788dd81a918a6d923c83d220b
Full Text :
https://doi.org/10.1016/j.tetlet.2012.02.079