Effects of energy metabolism modifiers on cyclophosphane toxicity forDaphnia magna

The effects of various energy metabolism modifiers and their combinations on cyclophosphane toxicity are examined in the fresh-water crustaceaDaphnia magna. The role of acute energy deficiency in the development of paralyzing effect of cyclophosphane is demonstrated. Transporting forms of succinic acid and combinations of carbonic acids with NAD exhibit high protective activity, while glucose reduces protective activity of NAD and sensitizing activity of amino acids.