Total synthesis of nephritogenic glycopeptide, nephritogenoside

Nephritogenoside (1), proposed as a nephritogenic triglycosylhenicosapeptide with asparagine N-α-glycoside linkage, was first synthesized by the coupling of triglycosyldipeptide active ester with the nonadecapeptide (3–21) using allyloxycarbonyl group as the final protecting group. A β-anomeric glycopeptide was also prepared.