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Determination of fetal DNA fraction from the plasma of pregnant women using sequence read counts
- Source :
- Prenatal Diagnosis. 35:810-815
- Publication Year :
- 2015
- Publisher :
- Wiley, 2015.
-
Abstract
- ObjectiveThis study introduces a novel method, referred to as SeqFF, for estimating the fetal DNA fraction in the plasma of pregnant women and to infer the underlying mechanism that allows for such statistical modeling.MethodsAutosomal regional read counts from whole-genome massively paralle
Details
- ISSN :
- 01973851
- Volume :
- 35
- Database :
- OpenAIRE
- Journal :
- Prenatal Diagnosis
- Accession number :
- edsair.doi...........a0a71494400cbd974a705e6d805b3c03
- Full Text :
- https://doi.org/10.1002/pd.4615