Jaya Ant lion optimization-driven Deep recurrent neural network for cancer classification using gene expression data

Cancer is one of the deadly diseases prevailing worldwide and the patients with cancer are rescued only when the cancer is detected at the very early stage. Early detection of cancer is essential as, in the final stage, the chance of survival is limited. The symptoms of cancers are rigorous and therefore, all the symptoms should be studied properly before the diagnosis. Thus, an automatic prediction system is necessary for classifying cancer as malignant or benign. Hence, this paper introduces the novel strategy based on the JayaAnt lion optimization-based Deep recurrent neural network (JayaALO-based DeepRNN) for cancer classification. The steps followed in the developed model are data normalization, data transformation, feature dimension detection, and classification. The first step is data normalization. The goal of data normalization is to eliminate data redundancy and to mitigate the storage of objects in a relational database that maintains the same information in several places. After that, the data transformation is carried out based on log transformation that generates the patterns using more interpretable and helps fulfill the supposition, and to reduce skew. Also, the non-negative matrix factorization is employed for reducing the feature dimension. Finally, the proposed JayaALO-based DeepRNN method effectively classifies cancer based on the reduced dimension features to produce a satisfactory result. Thus, the resulted output of the proposed JayaALO-based DeepRNN is employed for cancer classification. The proposed JayaALO-based DeepRNN showed improved results with maximal accuracy of 95.97%, maximal sensitivity of 95.95%, and maximal specificity of 96.96%.