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Diastereoselective Synthesis of Indolindiones by Formal [5+1] Double Michael Cycloaddition to 4-Cinnamoylpyrrolediones

Authors :
V. O. Filimonov
Andrey N. Maslivets
P. A. Slepukhin
Michael Rubin
P. S. Silaichev
Source :
European Journal of Organic Chemistry. 2015:2739-2744
Publication Year :
2015
Publisher :
Wiley, 2015.

Abstract

An efficient [5+1] double Michael cycloaddition of enolates to 4-cinnamoylpyrrole-2,3-diones was investigated; the reaction allows for the highly diastereoselective assembly of indoline scaffolds with up to three contiguous stereogenic centers.

Details

ISSN :
1434193X
Volume :
2015
Database :
OpenAIRE
Journal :
European Journal of Organic Chemistry
Accession number :
edsair.doi...........9ec7acd0f868a9294bd7e0ec6c282990
Full Text :
https://doi.org/10.1002/ejoc.201500141