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Evaluating the Direct Economic Burden of Prolonged Mechanical Ventilation Among Patients With Acute Type A Aortic Dissection: a Propensity Score-matched Cohort Analysis

Authors :
Xizhen Huang
Liang-Wan Chen
Xu Zhang
Yanjuan Lin
Qiong Chen
Yanchun Peng
Sailan Li
Publication Year :
2021
Publisher :
Research Square Platform LLC, 2021.

Abstract

Background: Prolonged mechanical ventilation (PMV) among acute type A aortic dissection (AAAD) may affect the prognosis, but poorly known about the direct economic burden of PMV in patients with AAAD. The present study was contributing to filling this knowledge gap.Methods: This present study was a retrospective cohort study. Age, gender, payment methods, and postoperative complications were matched at a 1:1 ratio by using a propensity score analysis of AAAD patients. The direct economic burden was expressed as the median 1:1 differences of various hospital costs and length of stay (LOS). The Wilcoxon signed-rank tests were used to compare the difference of direct economic burden at mechanical ventilation (MV) and PMV patients.Results: A total of 464 patients, PMV occurred in 142(30.6%) patients, and 218 patients were enrolled in the matched analysis. The estimated total direct economic burden of PMV was $4970.28(PP < 0.05).Conclusions: Postoperative PMV was associated with increased economic burden among AAAD patients. This study emphasizes the need for early detection and management of PMV to reduce the economic burden.

Details

Database :
OpenAIRE
Accession number :
edsair.doi...........9e5f94e725003ad96054d031e2d063d6
Full Text :
https://doi.org/10.21203/rs.3.rs-754251/v1