PROTEOMIC CHARACTERIZATION OF STAGE C AND D HEART FAILURE: IDENTIFICATION OF A CORE PROTEIN SIGNATURE AND EFFECT OF TREATMENT

Proteomics may identify previously unsuspected regulatory pathways in heart failure with reduced ejection fraction (HFrEF). It remains uncertain how the proteome differs between Stages C and Stage D HF or how HF treatment alters the proteome. Following clinical matching of patients between Stages