O3‐13‐02: Premorbid IQ and intrinsic progression rate explain substantial variance in observed progression of Alzheimer's disease (AD) on multiple measures

negative for 34 subjects and positive for 36 (see figure). The visual assessments were negative and quantitative assessments were positive in 14 subjects. The visual assessments were positive and quantitative assessments were negative in 12 subjects. Conclusions: In this population, 26 of 96 subjects had discordant reads between the two methods. This may be a result of averaging regions in the quantitative assessment while only 1 region was required to be positive for the visual assessment. The quantitative threshold could be modified or visual assessment scores of 2 could be also considered positive but these alternative approaches would predominantly shift the balance between false positives and false negatives without substantially changing the discordant pairs.