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A Hybrid-Potential Free-Energy Study of the Isomerization Step of the Acetohydroxy Acid Isomeroreductase Reaction

Authors :
Flavien Proust-De Martin
Martin J. Field
and Renaud Dumas
Source :
Journal of the American Chemical Society. 122:7688-7697
Publication Year :
2000
Publisher :
American Chemical Society (ACS), 2000.

Abstract

The enzyme acetohydroxy acid isomeroreductase is a promising target for the design of herbicides because it is an essential enzyme for the synthesis of branched-chain amino acids in plants but is a...

Details

ISSN :
15205126 and 00027863
Volume :
122
Database :
OpenAIRE
Journal :
Journal of the American Chemical Society
Accession number :
edsair.doi...........9c28c0ead78b08038deb9ccb53ca5013
Full Text :
https://doi.org/10.1021/ja000414s