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Nickel(II)-catalyzed asymmetric alkylation of acyclic oxocarbenium ions with carboxylic acid derivatives
- Source :
- Chinese Chemical Letters. 32:1237-1240
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- A nickel(II)-catalyzed asymmetric alkylation of acyclic oxocarbenium ions generated in situ from corresponding acetals with carboxylic acid derivatives to prepare β-alkoxyl carbonyl moieties with diverse α-substituents has been disclosed. The method exhibited broad scope of acetals and carboxylic acid derivatives with excellent enantioselectivity and good functional group compatibility, and can be conducted in a gram-scale without obvious loss of efficiency.
- Subjects :
- chemistry.chemical_classification
Carboxylic acid
Oxocarbenium
chemistry.chemical_element
Compatibility (geochemistry)
02 engineering and technology
General Chemistry
Alkylation
010402 general chemistry
021001 nanoscience & nanotechnology
01 natural sciences
Combinatorial chemistry
0104 chemical sciences
Catalysis
Ion
chemistry.chemical_compound
Nickel
chemistry
Functional group
0210 nano-technology
Subjects
Details
- ISSN :
- 10018417
- Volume :
- 32
- Database :
- OpenAIRE
- Journal :
- Chinese Chemical Letters
- Accession number :
- edsair.doi...........9bc074bb43b83f5d5f11d83c06a17c76