Role of a 'Magic' Methyl: 2′-Deoxy-2′-α-F-2′-β-C-methyl Pyrimidine Nucleotides Modulate RNA Interference Activity through Synergy with 5′-Phosphate Mimics and Mitigation of Off-Target Effects

Subjects

Subjects :

Colloid and Surface Chemistry
General Chemistry
Biochemistry
Catalysis

Details

ISSN :

15205126 and 00027863

Volume :

144

Database :

OpenAIRE

Journal :

Journal of the American Chemical Society

Accession number :

edsair.doi...........9bbffe6abbd1ffd5c3b0eef69bdf8ab9

Full Text :

https://doi.org/10.1021/jacs.2c01679