Determination the levels of Bone Morphogentic Protein-2, P-selectin, substance P in β-Thalassemia major in Iraqi patients

The current study aimed to assess BMP-2, P-selectin, substance-p in s-thalassemia major patients in Babylon Province (Iraq), by enrolling individual of Arab ancestry. A total of 70 beta-thalassemia major patients and 30 normal individual were enrolled Family history. All patients were blood transfusion depend with age mean (14.1±0.7years). On the other hand the selected control do not have history of family for thalassemia and doesn’t have any disease with mean age (15.6±1.2years). The result revealed significant decrease in BMP-2 in beta-thalassemia major patients, and significant increase in P-selectin, substance P in beta-thalassemia major patients.