The significance of BCL6 abnormalities on fluorescence in situ hybridization (FISH) in chronic lymphocytic leukemia (CLL)

Authors :: Jeffrey A. Jones
Caitlin E. Coombes
Patrick Eulitt
Nyla A. Heerema
Qiuhong Zhao
Jennifer A. Woyach
Amy S. Ruppert
John C. Byrd
James S. Blachly
Amber Gordon
Lynne V. Abruzzo
Farrukh T. Awan
Leslie A. Andritsos
Source :: Journal of Clinical Oncology. 34:e19005-e19005
Publication Year :: 2016
Publisher :: American Society of Clinical Oncology (ASCO), 2016.
Abstract: e19005Background: The clinical course of CLL is variable but can be predicted in part by recurrent cytogenetic abnormalities. BCL6 functions as a transcriptional repressor during germinal center fo...

Subjects :: Cancer Research
medicine.diagnostic_test
business.industry
Chronic lymphocytic leukemia
fungi
Clinical course
food and beverages
Germinal center
medicine.disease
BCL6
Molecular biology
Oncology
immune system diseases
hemic and lymphatic diseases
Transcriptional Repressor
Medicine
Fish
business
Fluorescence in situ hybridization

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