Study on the 3D BioPrinting Technology of Hydrogel Tissue Engineering scaffolds

The precision molding capability of bio-3D printing is the basis for its application in tissue engineering, and SA-Gel two-component hydrogel has been widely used in bio-3D printing manufacturing of tissue engineering scaffolds. The extrusionability of hydrogel is the key point for the printing precision. In this paper, starting from the concentration, ratio, rheology and cross-linking mode of hydrogel, the research ideas of “single factor independent analysis” and multi-factor comprehensive application are adopted to solve the printing accuracy. Through the research and screening of printing parameters and printing compensation technology, the accurate printing of the 1D line segment and 2D grid structure at 45°C for SA-Gel hydrogel with 2% and 8% mass respectively have been achieved.